研究業績

原著論文
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2024年 2023年 2022年 2021年 2020年 2019年 2018年 2017年 2016年 2015年 2014年 2013年

総説・資料など

学会発表

講演



原著論文

2024年

Yuasa H, Miyazaki K, Kido T, Nishino K, Shiotsu M, Fukuwatari T, Suka M, Nagao M, and Kambe T.
Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: in vitro and in vivo.
FASEB J 2024;38:e70025 [Abstract]

Klausing AD, Fukuwatari T, DeAngeli N, Bucci DJ, and Schwarcz R.
Adrenalectomy exacerbates stress-induced impairment in fear discrimination: a causal role for kynurenic acid?
Biochem Pharmacol 2024;228:116350 [Abstract]

Mizutani A, Nishikawa T, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, and Fukuwatari T.
Chronic endurance exercise impairs niacin nutritional status in mice.
J Nutr Sci Vitaminol 2024;7:185-92. [Abstract]

Mizutani A, Goto C, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, and Fukuwatari T.
Chronic ethanol intake impairs niacin nutritional status in mice.
J Nutr Sci Vitaminol 2024;70:1-8. [Abstract]



2023年

Mizutani A, Sato M, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, and Fukuwatari T.
Establishment of model mice to evaluate low niacin nutritional status.
J Nutr Sci Vitaminol 2023;69:305-13. [Abstract]



2022年

Furuya S, and Fukuwatari T.
Physiological functions of proteinogenic amino acid.
J Nutr Sci Vitaminol 2022;68:S28-30. [Abstract]



2021年

Hirai M, Hatayama S, Kimata M, Shibata K, and Fukuwatari T.
Effects of B-group vitamin administration on daily change in urine 2-oxo acids in young Japanese women.
J Nutr Sci Vitaminol 2021;67:63-7. [Abstract]



2020年

Ueno M, Tomita T, Arakawa H, Kakuta T, Yamagishi T, Terakawa J, Daikoku T, Horike S, Si S, Kurayoshi K, Ito C, Kasahara A, Tadokoro Y, Kobayashi M, Fukuwatari T, Tamai I, Hirao A, and Ogoshi T.
Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples.
Commun Chem 2020;3:183. doi.org/10.1038/s42004-020-00430 [Abstract]

Seura T, and Fukuwatari T.
Differences in gut microbial patterns associated with salivary biomarkers in young Japanese adults.
Biosci Microbiota Food Health 2020;39:243-9. [Abstract]

Klausing AD, Fukuwatari T, Bucci DJ, and Schwarcz R.
Stress-induced impairment in fear discrimination is causally related to increased kynurenic acid formation in the prefrontal cortex.
Psychopharmacology 2020;237:1931-41. [Abstract]

Hornigold N, Dunn KR, Craven RA, Zougman A, Trainor S, Shreeve R, Brown J, Sewell H,
Shires M, Knowles M, Fukuwatari T, Maher ER, Burns J, Bhattarai S, Menon M, Brazma A,
Scelo G, Feulner L, Riazalhosseini Y, Lathrop M, Harris A, Selby PJ, Banks RE, and Vasudev NS.
Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.
Br J Cancer 2020;123:137-47. [Abstract]



2019年

Ao M, Nagae A, Makino S, Kitagawa M, Kumode M, Kuwabara A, Fukuwatari T, Miyawaki T, and Tanaka K.
Gastric and jejunal enteral feeding differently affect vitamin B12 status in subjects with severe motor and intellectual disabilities.
J Nutr Sci Vitaminol 2019;65:541-44. [Abstract]

Seura T, and Fukuwatari T.
Japanese diet score is associated with gut microbiota composition in young Japanese adults.
J Nutr Sci Vitaminol 2019;65:414-20. [Abstract]

Sekine A, and Fukuwatari T.
Acute liver failure increases kynurenic acid production in rat brain via changes in tryptophan metabolism in the periphery.
Neuroscience Lett 2019;701:14-9. [Abstract]

Iwakawa H, Fukui T, Fukuwatari T, Bamba S, Sasaki M, Ysujikawa T, Doi Y, and Shibata K.
Blood concentrations and renal clearance of water-soluble vitamins in outpatients with ulcerative colitis.
Biomedical Reports 2019;10:202-10. [Abstract]



2018年

Moriya A, Fukuwatari T, and Shibata K.
A suitable diet for recovery from starvation is a high fat diet, but not a high protein diet, in rats.
J Nutr Sci Vitaminol 2018;64:412-24. [Abstract]

Ohtsuki M, Shibata K, Fukuwatari T, Sasaki Y, and Nakai K.
Randomized controlled trial of educational intervention to increase consumption of vegetables by Japanese university students.
Health Education 2018;118:209-303. [Abstract]

Shibui Y, Matsumoto H, Masuzawa Y, Ohishi T, Fukuwatari T, Shibata K, and Sakai R.
Thirteen week toxicity study of dietary L-tryptophan in rats with a recovery period of 5 weeks.
J Appl Toxicol 2018;38:552-63. [Abstract]



2017年

Seura T, Yoshino Y, and Fukuwatari T.
The relationship between habitual dietary intake and gut microbiota in young Japanese women.
J Nutr Sci Vitaminol 2017;63:396-404. [Abstract]

Urata T, Mori N, and Fukuwatari T.
Vagus nerve is involved in the changes in body temperature induced by intragastric administration of 1,8-cineole via TRPM8 in mice.
Neurosci Lett 2017;650:65-70. [Abstract]



2016年

Iwakawa H, Nakamura Y, Fukui T, Fukuwatari T, Ugi S, Maegawa H, Doi Y, and Shibata K.
Concentrations of water-soluble vitamins in blood and urinary excretion in patients with Diabetes Mellitus.
Nutr Metab Insight 2016;9:85-92. [Abstract]

Masuda H, Mori N, Hirobe Y, Tanaka R, Chino D, Watanabe T, and Fukuwatari T.
Different contribution of non-volatile and volatile components in winter savory (Satureja Montana L.) to changes in human body temperature.
Food Sci Technol Res 2016;22:817-27. [Abstract]

Sekine A, Kuroki Y, Urata T, Mori N, and Fukuwatari T.
Inhibition of large neutral amino acid transporters suppresses kynurenic acid production via inhibition of kynurenine uptake in rodent brain.
Neurochem Res 2016;41:2256-66. [Abstract]

Mori N, Urata T, and Fukuwatari T.
Thermal conditions influence changes in body temperature induced by intragastric administration of capsaicin in mice.
Biosci Biotechnol Biochem 2016;80:1615-22. [Abstract]

Shibata K, Nakata C, and Fukuwatari T.
High performance liquid chromatographic method for profiling 2-oxo acids in urine and its application in evaluating vitamin status in rats.
Biosci Biotechnol Biochem 2016;80:304-12. [Abstract]

Masuda H, Mori N, Matsui K, Wakimura S, Chino D, and Fukuwatari T.
Contribution of volatile components in winter savory (Satureja montana L.) to changes in body temperature in humans who experience cold sensitivity.
Food Sci Technol Res 2016;22:135-44. [Abstract]



2015年

Shibata K, Morita N, Kawamura T, Tsuji A, and Fukuwatari T.
Effects of fatty liver induced by excess orotic acid on B-group vitamin concentrations of liver, blood, and urine in rats.
J Nutr Sci Vitaminol 2015;61:355-61. [Abstract]

Shibata K, Hirose J, and Fukuwatari T.
Method for evaluation of the requirements of B-group vitamins using tryptophan metabolites in human urine.
Int J Tryptophan Res 2015;8:31-9. [Abstract]

Shibata K, Fukuwatari T, and Kawamura T.
Conversion percentage of tryptophan to nicotinamide is higher in rice protein diet than in wheat protein diet in rats.
Int J Tryptophan Res 2015;8:19-25. [Abstract]

Takahashi K, Fukuwatari T, and Shibata K.
Exercise and a high fat diet synergistically increase the pantothenic acid requirement in rats.
J Nutr Sci Vitaminol 2015;61:215-21. [Abstract]

Sekine A, Okamoto M, Kanatani Y, Sano M, Shibata K, and Fukuwatari T
Amino acids inhibit kynurenic acid formation via suppression of kynurenine uptake or kynurenic acid synthesis in rat brain in vitro.
SpringerPlus 2015;4:48 doi:10.1186/s40064-015-0826-9 [Abstract]

Shibata K, Kobayashi R, and Fukuwatari T.
Vitamin B1 deficiency inhibits the inceased conversion of tryptophan to nicotinamide in severe food-restricted rats.
Biosci Biotechnol Biochem 2015;79:103-8. [Abstract]



2014年

Shibata K, and Fukuwatari T.
Tissue vitamin concentrations are maintained at constant by changing the urinary excretion rate of vitamins in rats restricted food intake.
Biosci Biotechnol Biochem 2014;78:2102-9. [Abstract]

Shibata K, and Fukuwatari T.
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
J Nutr Sci Vitaminol 2014;60:334-9. [Abstract]

Maeta A, Sano M, Fukuwatari T, and Shibata K.
Simultaneous measurement of nicotinamide and its catabolites, nicotinamide N-oxide, N1-methyl-2-pyridone-5-carboxamide, and N1-methyl-4-pyridone-3-carboxamide in mice urine.
Biosci Biotechnol Biochem 2014;78:1306-9. [Abstract]

Shibata K, Hirose J, and Fukuwatari T.
Relationship between urinary concentrations of nine water-soluble vitamins and their vitamin intakes in Japanese adult males.
Nutr Metab Insight 2014;7:61-75. [Abstract]

Maeta A, Sano M, Fukuwatari T, Funakoshi H, Nakamura T, and Shibata K.
Contributions of tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase to the conversion of D-tryptophan to nicotinamide analyzed by using tryptophan 2,3-dioxygenase-knockout mice.
Biosci Biotechnol Biochem 2014;78:878-81. [Abstract]

Shibata K, Ohno T, Sano M, and Fukuwatari T.
Urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.
J Nutr Sci Vitaminol 2014;60:261-8. [Abstract]

Hiratsuka C, Sano M, Fukuwatari T, and Shibata K.
Time-dependent effects of L-tryptophan administration on urinary excretion of L-tryptophan metabolites.
J Nutr Sci Vitaminol 2014;60:255-60. [Abstract]

Shibata K, Fukuwatari T, and Suzuki C.
Pharmacological doses of nicotinic acid and nicotinamide are independently metabolized in rats.
J Nutr Sci Vitaminol 2014;60:86-93. [Abstract]

Nomura K, Tatsumi S, Miyagawa A, Shiozaki Y, Sasaki S, Kaneko I, Ito M, Kido S, Segawa H, Sano M, Fukuwatari T, Shibata K, and Miyamoto KI.
Hepatectomy-related hypophosphatemia: A novel phosphaturic factor in the liver-kidney axis.
J Am Soc Nephrol 2014;25:761-72. [Abstract]

Shibata K, Nakata C, and Fukuwatari T.
Moderate food restriction suppresses the conversion of L-tryptophan to nicotinamide in weaning rats.
Biosci Biotechnol Biochem 2014;78:478-81. [Abstract]

今井 具子,辻 とみ子,山本 初子,福渡 努,柴田 克己
秤量法食事記録調査より求めた小学生、大学生、高齢者のミネラル摂取量及び食品群別寄与率の比較
栄養学雑誌 2014;72:51-66. [Abstract]

Shibata K, Tachiki A, Horiuchi H, Mukaeda K, Morioka M, Fukuwatari T, Sasaki S, and Jinno Y.
More than 50% in pregnant Japanese women with an intake of 150 μg dietary folate per 1,000 kcal can maintain over the cut-off value.
J Nutr Sci Vitaminol 2014;60:1-8. [Abstract]



2013年

Shibata K, Imai S, Nakata C, and Fukuwatari T.
The effects of glycine, L-threonine, and L-cystine supplementation to a 9% casein diet on the conversions of L-tryptophan to nicotinamide and to serotonin in rats.
J Nutr Sci Vitaminol 2013;59:533-40. [Abstract]

Shibata K, Inomoto K, Nakata C, and Fukuwatari T.
Pantothenic acid deficiency may increase the urinary excretion of 2-oxo acids and nicotinamide catabolites in rats.
J Nutr Sci Vitaminol 2013;59:509-15. [Abstract]

Shibata K, Fukuwatari T, and Sasaki S.
Nutritional status of water-soluble vitamins did not differ according to intake levels of wheat and wheat alternatives and rice and rice alternatives as a staple food in pregnant Japanese women.
Nutr Metab Insights 2013;6:51-7. [Abstract]

Shibata K, Tsuji T, and Fukuwatari T.
Intake and urinary amounts of biotin in Japanese elementary school children, college students, and elderly persons.
Nutr Metab Insights 2013;6:43-50. [Abstract]

Shibata K, Morita N, Shibata Y, and Fukuwatari T.
Enzymes that control the conversion of L-tryptophan-nicotinamide and the urinary excretion ratio (N1-methyl-2-pyridone-5-carboxamide +N1-methyl-4-pyridone-3-carboxamide)/N1-methylnicotinamide in mice.
Biosci Biotechnol Biochem 2013;77:2105-11. [Abstract]

Tsuji A, Nakata C, Sano M, Fukuwatari T, and Shibata K.
L-Tryptophan metabolism in pregnant mice fed a high L-tryptophan diet and the effect on maternal, placental and fetal growth.
Int J Tryptophan Res 2013;6: 21-33. [Abstract]

Shibata K, and Fukuwatari T.
High D(+)-fructose diet adversely affects testicular weight gain in weaning rats - protection by moderate D(+)-glucose diet.
Nutr Metab Insights 2013;6:29-31. [Abstract]

Maeta A, Fukuwatari T, Funakoshi H, Nakamura T, and Shibata K.
Tryptophan-restriction diets help to maintain L-tryptophan homeostasis in tryptophan 2,3-dioxygenase knockout mice.
Int J Tryptophan Res 2013;6:55-65. [Abstract]

Moriya A, Fukuwatari T, and Shibata K.
Excess vitamin intake before starvation does not affect body mass, organ mass or blood variables but affects urinary excretion of riboflavin in starving rats.
Nutr Metab Insights 2013;6:23-8. [Abstract]

Shibata K, Tachiki A, Mukaeda K, Fukuwatari T, Sasaki S, and Jinno Y.
Changes in plasma pyridoxal 5'-phosphate concentration during pregnant stages in Japanese women.
J Nutr Sci Vitaminol 2013;59:343-6. [Abstract]

Shibata K, and Fukuwatari T.
Values for evaluating the nutritional status of water-soluble vitamins in humans.
J Integrated OMICS 2013;3:60-9. [Abstract]

Terakata M, Fukuwatari T, Kadota E, Sano M, Kanai M, Nakamura T, Funakoshi H, and Shibata K.
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
J Nutr 2013;143:1046-51. [Abstract]

Hiratsuka C, Fukuwatari T, Sano M, Saito K, Sasaki S, and Shibata K.
Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects.
J Nutr 2013;143:859-66. [Abstract]

Shibata K, Shimizu A, and Fukuwatari T.
Vitamin B1 deficiency does not affect the liver concentrations of the other seven kinds of B-group vitamins in rats.
Nutr Metab Insight 2013;6:1-10. [Abstract]

Imai E, Sano M, Fukuwatari T, and Shibata K.
Changes of B-group vitamin status in adenine-induced chronic renal failure rats.
Biosci Biotechnol Biochem 2013;77:1108-10. [Abstract]

Shibata K, Fukuwatari T, Sasaki S, Sano M, Suzuki K, Hiratsuka C, Aoki A, and Nagai C.
Urinary excretion levels of water-soluble vitamins in pregnant and lactating women in Japan.
J Nutr Sci Vitaminol 2013;59:178-86. [Abstract]

Shibata K, Fukuwatari T, Higashiyama S, Sugita C, Azumano I, and Onda M.
Pantothenic acid re-feeding diminishes the liver, perinephrical and plasma fats accumulated by pantothenic acid-deficiency and/or ethanol consumption.
Nutrition 2013;29:796-801. [Abstract]

Shibata K, Kaneko M, and Fukuwatari T.
D-Pantethine has equivalent vitamin activity as D-pantothenic acid for recovering from a deficiency of D-pantothenic acid in rats.
J Nutr Sci Vitaminol 2013;59:93-99. [Abstract]

Shibata K, and Fukuwatari T.
The body vitamin B1 levels of rats fed a diet containing a minimum requirement of vitamin B1 is reduced by exercise.
J Nutr Sci Vitaminol 2013;59:87-92. [Abstract]

Shibata K, Sugita C, Sano M, and Fukuwatari T.
Urinary excretions of B-group vitamins reflect the nutritional status of B-group vitamins in rats.
J Nutr Sci 2013;2: DOI: http://dx.doi.org/10.1017/jns.2013.3 [Abstract]

Shibata K, Kondo R, Sano M, and Fukuwatari T.
Dietary valproate increases the conversion of tryptophan to nicotinamide in rats.
Biosci Biotechnol Biochem 2013;77:295-300. [Abstract]


総説・資料など

2024年

畑山 翔,水谷 天音,福渡 努
ナイアシン不足モデルマウスの確立とナイアシン栄養状態を低下させる因子の解明
臨床化学 2024;53: in press


2023年

福渡 努
皮膚美容とサプリメント:皮膚とビタミン
日本食品安全協会会誌 2023;18:93-98.



2022年

福渡 努
トリプトファン−NAD経路代謝産物キヌレン酸と脳神経機能
ビタミン 2022;96:391-6.



2020年

Fukuwatari T.
Possibility of amino acid treatment to prevent psychiatric disorders via modulation of tryptophan metabolite kynurenic acid production.
Nutrients 2020;12:E1403. doi:10.3390/nu12051403 [Abstract]

福渡 努
美肌と栄養:美肌に関係する水溶性ビタミンの生理機能
美容皮膚医学 BEAUTY 2020;3:44-9.



2019年

福渡 努
ビタミンと健康機能:ナイアシン
日本食品安全協会誌 2019;4:186-91.



2018年

福渡 努
ビタミン供給源としての卵
日食科工誌 2018;65:325-30. [Abstract]



2017年

福渡 努
ビタミンの欠乏・不足をどう考えるか?−水溶性ビタミン Overview−
臨床栄養 2017;130:160-164.



2016年

関根 愛莉,黒木 裕介,浦田 朋実,森 紀之,福渡 努
大型中性アミノ酸トランスポーター阻害剤による脳内キヌレン酸産生の抑制
アミノ酸研究 2016;10:61-5.

Shibata K, and Fukuwatari T.
Organ correlation with tryptophan metabolism obtained by analyses of TDO-KO and QPRT-KO mice.
Int J Tryptophan Res 2016;9:1-7. doi: 10.4137/IJTR.S37984. [Abstract]



2013年

福渡 努
尿成分分析による栄養素摂取量および栄養状態の評価
ILSI JAPAN 2013;113:8-15.

Fukuwatari T, and Shibata K.
Nutritional aspect of tryptophan metabolism.
Int J Tryptophan Res 2013;6:S3-S8. [Abstract]

Shibata K, Fukuwatari T, Imai E, Hayakawa T, Watanabe F, Takimoto H, Watanabe T, and Umegaki K.
Dietary reference intakes for Japanese 2010: Water-soluble Vitamins.
J Nutr Sci Vitaminol 2013;59:S67-S82. [Abstract]

福渡 努
尿を生体指標として利用した水溶性ビタミンの栄養評価法の確立
ビタミン 2013;87:17-20. [Abstract]



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 福渡 努
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